Publications

Historical H1N1 Influenza Virus Imprinting Increases Vaccine Protection by Influencing the Activity and Sustained Production of Antibodies Elicited at Vaccination in Ferrets

Francis ME, McNeil M, Dawe NJ, Foley MK, King ML, Ross TM, Kelvin AA

2019 Sept; 7(4): 133

* Conceived and designed the study, secured funding, directed experiments, and wrote the manuscript.

Back to the Future for Influenza Preimmunity-Looking Back at Influenza Virus History to Infer the Outcome of Future Infections

Francis ME, King ML, Kelvin AA*

2019 Jan; 11(2): 122

* Conceived the manuscript, wrote the main sections, and directed manuscript writing from the students.

ZIKATracker: A mobile App for reporting cases of ZIKV worldwide

Kelvin AA*, Banner D, Pamplona L, Alencar C, Rubino S, Heukelbach J.

2016 Feb; 10(2):113-5

* Wrote this manuscript and designed and executed the app that is described in the text in collaboration with development from mWater.

Zika virus outbreak in Brazil

Heukelbach J, Alencar CH, Kelvin AA*, De Oliveira WK, Pamplona de Goes CL.

2016; 10(2):116-20

* Wrote the Zika history and host responses sections.

Probable Hospital Cluster of H7N9 Influenza Infection

Farooqui A, Liu W, Kelvin DJ, Zeng T, Liu Y, Zhang L, Khan A, Wu X, Wu R, Wu S, Huang L, Cai Y, Kelvin AA*, Paquette SG, Hu K, Zheng N, Chen H, Xu S, Lin C, Sun P, Yao Z, Wang J, Ma H, Zhu Z, Lin P, Chen W, Fang X, Bermejo-Martin JF, Leon AJ.

2016 Feb 11; 374(6):596-8

* Participated in study design and data analysis.

Assessment of antiviral properties of Peramivir against H7N9 avian influenza virus in an experimental mouse model

Farooqui A, Huang L, Wu S, Cai Y, Su M, Lin P, Chen W, Fang X, Zhang L, Liu Y, Zheng T, Paquette SG, Khan A, Kelvin AA* and Kelvin DJ.

2015 Dec; 59(12):7255-64

* Participated in study design and data analysis.

Pathogenic influenza B virus in the ferret model establishes lower respiratory tract infection

Huang SS, Banner D, Paquette SG, Leon AJ, Kelvin AA*, and Kelvin DJ

2014 Oct; 95(Pt 10):2127-39. PMCID:PMC4165929

* Designed the study and experiments. Co-analyzed data and co-wrote the manuscript.

Lack of group X secreted phospholipase A(2) increases survival following pandemic H1N1 influenza infection

Kelvin AA*, Degousee N, Banner D, Stefanski E, Leomicronn AJ, Angoulvant D, Paquette SG, Huang SS, Danesh A, Robbins CS, Noyan H, Husain M, Lambeau G, Gelb M, Kelvin DJ, and Rubin BB

2014 Apr; 454-455:78-92. PMCID:PMC4106042

* Designed some experiments. Analyzed the data. Wrote the manuscript.

Next-generation sequencing and bioinformatic approaches to detect and analyze influenza virus in ferrets

Lin Z, Farooqui A, Li G, Wong GK, Mason AL, Banner D, Kelvin AA*, Kelvin DJ, and Leon AJ

2014; 8(4):498-509

* Participated in data analysis and study design.

Impaired heterologous immunity in aged ferrets during sequential influenza A H1N1 infection

Paquette SG, Huang SS, Banner D, Xu L, Leon A, Kelvin AA*, and Kelvin DJ

2014 Sep; 464-465:177-83. PMCID:PMC4157083

* Co-designed the project and experiments. Supervised study progress. Co-analyzed the data and co-wrote the manuscript.

CXCL14 deficiency does not impact the outcome of influenza or Escherichia coli infections in mice

Sidahmed AM, Leon AJ, Banner D, Kelvin AA*, Rowe T, Boudakov I, Degousse N, Rubin BB, and Kelvin DJ

2014 Oct; 8(10):1301-6

* Co-analyzed the data and co-wrote the manuscript.

Sequencing, annotation, and characterization of the influenza ferret infectome

Leon AJ, Banner D, Xu L, Ran L, Peng Z, Yi K, Chen C, Xu F, Huang J, Zhao Z, Lin Z, Huang SH, Fang Y, Kelvin AA*, Ross TM, Farooqui A, and Kelvin DJ

2013 Feb; 87(4):1957-66. PMCID:PMC3571481

* Co-designed the experiments. Participated in data analysis. 

Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs

Zhu H, Wang D, Kelvin DJ, Li L, Zheng Z, Yoon SW, Wong SS, Farooqui A, Wang J, Banner D, Chen R, Zheng R, Zhou J, Zhang Y, Hong W, Dong W, Cai Q, Roehrl MH, Huang SS, Kelvin AA*, Yao T, Zhou B, Chen X, Leung GM, Poon LL, Webster RG, Webby RJ, Peiris JS, Guan Y, and Shu Y

2013 Jul 12; 341(6142):183-6

* Co-analyzed the data. 

The current state of H5N1 vaccines and the use of the ferret model for influenza therapeutic and prophylactic development

Banner D and Kelvin AA*

2012 Jun; 6(6):465-9

* Designed the manuscript. Co-wrote the manuscript.

Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model

Cameron MJ, Kelvin AA*, Leon AJ, Cameron CM, Ran L, Xu L, Chu YK, Danesh A, Fang Y, Li Q, Anderson A, Couch RC, Paquette SG, Fomukong NG, Kistner O, Lauchart M, Rowe T, Harrod KS, Jonsson CB, and Kelvin DJ

2012; 7(9):e45842. PMCID:PMC3454321

* Participated in study design and data analysis. Co-wrote the manuscript.

Seasonal H1N1 influenza virus infection induces cross-protective pandemic H1N1 virus immunity through a CD8-independent, B cell-dependent mechanism

Fang Y, Banner D, Kelvin AA*, Huang SS, Paige CJ, Corfe SA, Kane KP, Bleackley RC, Rowe T, Leon AJ, and Kelvin DJ

2012 Feb; 86(4):2229-38. PMCID:PMC3302411

* Participated in study design and data analysis. Co-wrote the manuscript.

Influenza monitoring in Sardinia, Italy identifies H3 subtype in Mediterranean wild migratory birds

Kelvin AA*, Meloni D, Sansonetti P, Borghetto I, Rowe T, Santangelo R, Pisu D, Cameron CM, Paglietti B, Banner D, Farooqui A, Marongiu P, Santona A, Fadda G, Kelvin DJ, and Rubino S

2012; 6(11):786-97

* Co-designed the project. Designed the experiments. Supervised study progress. Participated in data generation. Co-analyzed the data and co-wrote the manuscript.

Interleukin-6 is a potential biomarker for severe pandemic H1N1 influenza A infection

Paquette SG, Banner D, Zhao Z, Fang Y, Huang SS, Leomicronn AJ, Ng DC, Almansa R, Martin-Loeches I, Ramirez P, Socias L, Loza A, Blanco J, Sansonetti P, Rello J, Andaluz D, Shum B, Rubino S, de Lejarazu RO, Tran D, Delogu G, Fadda G, Krajden S, Rubin BB, Bermejo-Martin JF, Kelvin AA*, and Kelvin DJ

2012; 7(6):e38214. PMCID:PMC3367995

* Co-designed the project. Designed the experiments. Supervised study progress. Co-analyzed the data and co-wrote the manuscript.

Early gene expression events in ferrets in response to SARS coronavirus infection versus direct interferon-alpha2b stimulation

Danesh A, Cameron CM, Leon AJ, Ran L, Xu L, Fang Y, Kelvin AA*, Rowe T, Chen H, Guan Y, et al

2011 Jan 5; 409(1):102-12

* Participated in study design and data analysis.

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility

de l, V#, Kelvin AA#, Dunican DJ, McFarlane C, Burrows JF, Jaworski J, Stevenson NJ, Dib K, Rappoport JZ, Scott CJ, et al

2011; 2:259. PMCID:PMC3072070

# Co-first author

* Wrote the manuscript and designed the experiments. Conducted the experiments and analyzed the data.

Comparative analyses of pandemic H1N1 and seasonal H1N1, H3N2, and influenza B infections depict distinct clinical pictures in ferrets

Huang SS, Banner D, Fang Y, Ng DC, Kanagasabai T, Kelvin DJ, and Kelvin AA*

2011; 6(11):e27512. PMCID:PMC3217968

* Co-designed the project. Designed the experiments. Supervised study progress. Co-analyzed the data and co-wrote the manuscript.

Outbreak of Chikungunya in the Republic of Congo and the global picture

Kelvin AA*

2011 Jun; 5(6):441-4

* Designed and wrote the manuscript.

Inflammatory cytokine expression is associated with chikungunya virus resolution and symptom severity

Kelvin AA*, Banner D, Silvi G, Moro ML, Spataro N, Gaibani P, Cavrini F, Pierro A, Rossini G, Cameron MJ, Bermejo-Martin JF, Paquette SG, Xu L, Danesh A, Farooqui A, Borghetto I, Kelvin DJ, Sambri V, and Rubino S

2011 Aug; 5(8):e1279. PMCID:PMC3156690

* Co-designed the project. Designed the experiments. Supervised study progress. Participated in data generation. Co-analyzed the data. Wrote the manuscript.

Outbreak of cholera in the Republic of Congo and the Democratic Republic of Congo, and cholera worldwide

Kelvin AA*

2011 Oct; 5(10):688-91

* Designed and wrote the manuscript.

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression

McFarlane C, Kelvin AA*, de l, V, Govender U, Scott CJ, Burrows JF, and Johnston JA

2010 Apr 15; 70(8):3329-39

* Designed and conducted key experiments. Analyzed data.

In vivo ribavirin activity against severe pandemic H1N1 Influenza A/Mexico/4108/2009

Rowe T, Banner D, Farooqui A, Ng DC, Kelvin AA*, Rubino S, Huang SS, Fang Y, and Kelvin DJ

2010 Dec; 91(Pt 12):2898-906

* Co-analyzed data. Co-wrote the manuscript.

Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11

Stevenson NJ, McFarlane C, Ong ST, Nahlik K, Kelvin A*, Addley MR, Long A, Greaves DR, O'Farrelly C, and Johnston JA

2010 Nov 5; 584(21):4469-74

* Designed and conducted key experiments. Analyzed data.

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity

Burrows JF, Kelvin AA*, McFarlane C, Burden RE, McGrattan MJ, de l, V, Govender U, Quinn DJ, Dib K, Gadina M, Scott CJ, and Johnston JA

2009 Apr 3; 284(14):9587-95. PMCID:PMC2666611

* Designed and conducted key experiments. Analyzed data. Co-wrote the manuscript.

Cloning, expression and characterization of ferret CXCL10

Danesh A, Seneviratne C, Cameron CM, Banner D, Devries ME, Kelvin AA*, Xu L, Ran L, Bosinger SE, Rowe T, Czub M, Jonsson CB, Cameron MJ, and Kelvin DJ

2008 Mar; 45(5):1288-97

* Participated in data analysis and manuscript writing.

Defining the origins and evolution of the chemokine/chemokine receptor system

Devries ME, Kelvin AA*, Xu L, Ran L, Robinson J, and Kelvin DJ

2006 Jan 1; 176(1):401-15

* Participated in data analysis and manuscript writing.

The role of chemokines and chemokine receptors in alloantigen-independent and alloantigen-dependent transplantation injury

Devries ME, Hosiawa KA, Cameron CM, Bosinger SE, Persad D, Kelvin AA*, Coombs JC, Wang H, Zhong R, Cameron MJ, and Kelvin DJ

2003 Feb; 15(1):33-48

* Participated in manuscript writing.

Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus

Devries ME, Cao H, Wang J, Xu L, Kelvin AA*, Ran L, Chau LA, Madrenas J, Hegele RA, and Kelvin DJ

2003 Apr 4; 278(14):11985-94

* Conducted experiments. Participated in data analysis.

Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCR1

Barlic J, Andrews JD, Kelvin AA*, Bosinger SE, Devries ME, Xu L, Dobransky T, Feldman RD, Ferguson SS, and Kelvin DJ

2000 Sept; 1(3): 227-233

* Conducted key experiments. Participated in data analysis.